Sickle cell anemia victory: Zambian family finds hope at Hyderabad hospital as 7-year-old sister donates bone marrow to brother

“The rarity of such swift and courageous acts of donation, particularly in a scenario where detection and awareness of sickle cell disease are lacking in their home country,” Dr Thota commented.

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Bone marrow transplant

The severe sickle cell disease had cast a shadow over the boy’s daily life, marked by joint pain, haemoglobin depletion, and severe weakness.

Dr Thota explained the critical matching process involving Human Leukocyte Antigen (HLA) typing for both the donor and the recipient prior to bone marrow transplant. The sister’s stem cells presented a 100 percent match, offering a lifeline to her brother.

The procedure not only marked a medical milestone but also stood as a profound testimony to the power of familial bonds and selflessness.

The successful transplant is poised to alleviate the boy’s severe illness, transforming it into a milder form without further complications. Dr Thota assured that the boy can now lead a healthy life, free from the struggles imposed by sickle cell anemia.

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Sickle cell anemia

Dr Thota sheds light on the prevalence of sickle cell anemia in forested areas, especially in countries like India and African nations like Kenya and Zambia.

While it acts as a natural defense against malaria, it poses significant health challenges. He emphasised the lack of advanced care options, facilities, and awareness in African countries, leading families like the one from Zambia to seek treatment abroad.