Tamil Nadu fights scrub typhus outbreak, health department issues advisory

Scrub typhus — also known as bush typhus — is caused by a bacterium called Orientia tsutsugamushi, which is transmitted to humans through the bite of infected chiggers, a type of mite. It could be fatal, if not treated.

Published Jan 03, 2025 | 8:00 AMUpdated Jan 03, 2025 | 8:00 AM

Eschar in the left arm of patient with scrub typhus

Tamil Nadu’s Health Department has issued an advisory regarding an outbreak of scrub typhus, a rickettsial disease that is primarily transmitted through insect bites.

The disease, on an uptick in the state, is characterised by fever, body aches, headache, and distinctive black rash-like lesions at the bite site.

Affected regions include Chennai, Tiruvallur, Kanchipuram, Chengalpattu, Ranipet, Vellore, and Tirupathur, with additional cases reported in several southern districts.

Understanding scrub typhus

Scrub typhus — also known as bush typhus — is caused by a bacterium called Orientia tsutsugamushi (formerly Rickettsia tsutsugamushi), which is transmitted to humans through the bite of infected chiggers, a type of mite.

This zoonotic disease affects people, particularly agricultural workers, living in areas with dense vegetation, those residing near bushes or forests, and campers and trekkers. While humans are accidental hosts, the disease’s transmission cycle involves rodents and mites.

Related: All you need to know about scrub typhus

Symptoms

Symptoms of scrub typhus typically appear within 1-2 weeks after the mite bite.

Scrub typhus - lifecyle

Lifecycle of scrub typhus.

Initial symptoms resemble those of the flu, high fever, headache, body pain, and rash. One of the hallmark signs of scrub typhus is the appearance of an “eschar,” a dark, necrotic ulcer that forms at the site of the bite.

If left untreated, the infection can lead to severe complications, including heart, lung, kidney, and neurological issues, potentially causing death.

Epidemiological insights

Scrub typhus is prevalent in the southern parts of Tamil Nadu, including areas around the Eastern Ghats, Western Ghats, and the Deccan Plateau.

The disease is also commonly reported in agricultural regions, where people come into close contact with the environment that hosts infected mites. Groups at risk include:

  • Agricultural workers: Those working in fields or near vegetation where mites thrive.
  • Rural population: People living in proximity to shrubs, bushes, and other vegetation.
  • Travellers: Individuals engaging in outdoor activities such as camping, trekking, or rafting in affected regions.
  • Pregnant women: Special care is advised for expectant mothers, as the disease may lead to complications.

Also Read: What is West Nile Fever?

Diagnosis and treatment

Timely diagnosis is crucial for effective management of scrub typhus. The disease can be identified through several laboratory methods, including:

  • IgM ELISA test: The most widely used diagnostic method, which detects antibodies produced in response to the infection.
  • PCR tests: Molecular diagnosis to detect the bacterial DNA.
  • Isolation: This can help confirm the diagnosis in clinical settings.

Once diagnosed, the treatment for scrub typhus varies, depending on the age and health condition of the patient. Standard medications include:

  • Adults: Doxycycline (200mg/day for 7 days) or Azithromycin (500mg single dose for 5 days).
  • Pregnant women: Azithromycin (500mg single dose for 5 days).
  • Children above 12 years: Azithromycin (10mg/kg single dose) or Doxycycline (4.5mg/kg/day in divided doses).
  • Children below 12 years: Azithromycin (10mg/kg single dose), as doxycycline is contraindicated in young children.

In cases of severe illness or complications such as cardiac, pulmonary, renal, or neurological issues, patients may need hospitalisation and intravenous antibiotics, such as doxycycline or azithromycin, before switching to oral therapy.

Prevention and control 

The health department outlined several preventive measures to curb the spread of scrub typhus:

  • Case detection and diagnosis: They include cases of undifferentiated fever lasting more than five days, with or without an eschar, and should be suspected as scrub typhus. Differential diagnoses for diseases such as dengue, malaria, pneumonia, and typhoid should be considered.
  • Vector control: The department recommends using cold fogging or ULV (Ultra Low Volume) spraying with pyrethrum-based insecticides to control chiggers in affected areas. Clearing bushes and vegetation near residential areas can help reduce the risk of mite exposure.
  • Rodent control: Rodents play a critical role in the lifecycle of the mite that transmits scrub typhus. Efforts to reduce rodent populations in affected regions are crucial.
  • Public awareness: A key aspect of prevention is educating the public, particularly in rural and high-risk areas, about the symptoms of scrub typhus and the importance of seeking medical care if symptoms arise. The health department has emphasized spreading awareness to prevent the disease from spreading further.

Also Read: Disease surveillance to get a boost in Kerala

Vigilance and action

The rise in scrub typhus cases has prompted the health department to heighten vigilance. District Health Officers and City Health Officers have been instructed to monitor the situation closely, ensure timely diagnosis and treatment, and carry out preventive measures to control the disease’s spread.

Public health campaigns, along with targeted interventions in rural and peri-urban areas, are expected to play a crucial role in mitigating the risk of further outbreaks.

As scrub typhus continues to affect various districts, the importance of rapid diagnosis, effective treatment, and preventive measures cannot be overstated.

Residents in high-risk areas have been urged to take necessary precautions and seek immediate medical attention if symptoms of scrub typhus are detected.

(Edited by Majnu Babu).

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