Why Is Guillain-Barré Syndrome surging in Maharashtra?

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By Sumit Jha

Feb 12, 2025

Maharashtra is battling an alarming outbreak of Guillain-Barré Syndrome (GBS), a rare autoimmune disorder, with Pune emerging as the epicenter.

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As of Tuesday, 11 February the state health authorities reported 192 suspected cases, 167 confirmed infections, and seven fatalities.

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GBS is a rare autoimmune disorder where the body attacks its peripheral nerves, leading to weakness, numbness, or paralysis. Severe cases require ICU care.

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The two common types of infections that can trigger GBS are respiratory infections and gastrointestinal infections.

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Health investigators have identified Campylobacter jejuni, a foodborne bacterium, as the primary trigger.

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Known to cause gastrointestinal infections that may escalate into GBS, the pathogen has been detected in water from several reverse osmosis (RO) plants in Pune.

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In Pune outbreak, it was due to a gastrointestinal infection caused by Campylobacter jejuni. 

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