Portable TB kit wins IISc researcher prestigious science prize in Europe

Karnataka By Vasudevan Sridharan November 30, 2022 Read the article

Ayushi Chauhan, a doctoral student at the Indian Institute of Science, designed a portable kit to detect drug-resistant tuberculosis.

[{"selector":"#anim-64feec99-c718-4d35-a1b9-0b93c6ce3476","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-fd4dfc9b-1f96-445a-8ffc-7a06a0f9d7df","keyframes":{"transform":["translate3d(0px, 39.23277%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-1193890d-917f-4243-a8bf-6396600b9578","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-14ce2cd1-8977-47aa-abec-2014e6fd43c5","keyframes":{"transform":["translate3d(0px, 141.64777%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-25634a0c-a7f7-43f0-8c3b-529bd9f9622a [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(-47.055856740112795%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Karnataka Read the article

The pocket-sized diagnostic kit was adjudged the third-best innovative idea presented at the Falling Walls Science Summit in Berlin in November 2022.

[{"selector":"#anim-3b26d974-1279-496d-bd34-2afa3138aaba","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-4bfd89ed-abe1-43f1-8e48-5670a7374121","keyframes":{"transform":["translate3d(0px, 43.35931%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-99871e93-2386-45dc-b99a-14bf673b77ff","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-3e645222-874a-4a1c-9db6-6c98bf093233","keyframes":{"transform":["translate3d(0px, 134.58883%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-9c01671f-d136-440b-b621-3ca209dac9be [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(-41.50390608615781%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Karnataka Read the article

As part of her PhD programme, Chauhan developed point-of-care diagnostic devices for various applications, the TB kit being one of them.

[{"selector":"#anim-5d22ec91-5605-4290-9589-a05cd89ec96d","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-604da138-111e-4c99-82bd-397a3c5b2c34","keyframes":{"transform":["translate3d(0px, 41.02094%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-ec4cab11-91db-4361-8653-381a53694a56","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-1601ffc8-0912-494f-addb-8962224ba894","keyframes":{"transform":["translate3d(0px, 147.08996%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-a8feb860-7861-4e79-8a81-fa222700dd12 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(-26.49290788195828%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Karnataka Read the article

Some 21 lakh TB cases were notified in India in 2021, representing 26 percent of the global incidence of the disease.

[{"selector":"#anim-4c5ca2ff-7e46-424c-b42e-68eea063ca69","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-54ca4830-44da-4a88-8c54-df30718ab127","keyframes":{"transform":["translate3d(0px, 36.89439%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-ef26b072-e592-443b-b3de-b71662c2de98","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-26e714c1-763f-4aa6-bee9-a62e0e985cac","keyframes":{"transform":["translate3d(0px, 157.81547%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-024beb44-b4af-49aa-8bda-660a27fc496c [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(-11.523437482546829%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Karnataka Read the article

It causes the largest number of deaths among all infectious diseases in the country, with an estimated average of 400,000 deaths annually.

[{"selector":"#anim-82a9ec56-3dbe-473a-97f6-aad9674e9c3d","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-8e87f4cd-702d-4f96-9180-a3d3753b90ec","keyframes":{"transform":["translate3d(0px, 40.33318%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-01f8cf86-e704-4087-8636-a7aded334a16","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-965267ef-ab4a-489b-9bf6-ca93b0b323b6","keyframes":{"transform":["translate3d(0px, 143.68856%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-ba7701a4-99e7-4f60-9bd2-5b9f7815f6d8 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(-31.26863805731298%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Karnataka Read the article

What is alarming, WHO figures suggest, is that the number of drug-resistant TB cases is increasing in the country.

[{"selector":"#anim-2f5b6d33-2eb3-4706-8c14-1cfcb641d7c2","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-69233eef-001f-4fc0-b4e7-841cf2d8d905","keyframes":{"transform":["translate3d(0px, 36.20663%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-85e39d9c-7c7f-449c-ad30-2c28e2295686","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-ffef0199-cf91-43bc-b5d6-67a567b7b6f7","keyframes":{"transform":["translate3d(0px, 153.12796%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-8244da29-69db-456f-977a-10ed30cf5053 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(-30.324074018053853%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Karnataka Read the article

Early diagnosis is essential to halt the progress of TB infection in a patient.

[{"selector":"#anim-5f4c0e82-9c17-4479-b1f9-35fffe50405c","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-224f6749-6124-4848-a7da-0af0433ec1c9","keyframes":{"transform":["translate3d(0px, 32.08008%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-7dbe99d9-4502-42e9-b62d-8d79d903a0a6","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-d83ff5b3-5296-46aa-821a-02a99b00d1ec","keyframes":{"transform":["translate3d(0px, 169.13578%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-7dc51056-3629-417f-abfe-44dc7774a203 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(-14.599609181198103%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Karnataka Read the article

It is here that Chauhan’s kit can come into play in a big way; it proposes to detect drug-resistant TB in its early stages.

[{"selector":"#anim-a2f12af1-f182-41a4-9f04-81f80fc69e35","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-659742a8-322a-4329-8238-2f50ece07c34","keyframes":{"transform":["translate3d(0px, 40.33318%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-b17ec442-b6da-4ee4-a273-f5404da0c244","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-708f712c-4d90-4828-be22-f2db96852f6a","keyframes":{"transform":["translate3d(0px, 144.06908%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-09b36e09-b66c-467b-b954-1414e101c611 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(-32.90681826798828%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Karnataka Read the article