How hormonal imbalances in metabolic syndrome fuel women’s cancer risk

Veni E N

Oct 22, 2025

Health

Health

Women with metabolic syndrome face a markedly higher risk of gynaecologic cancers, especially endometrial, ovarian, and cervical, according to a 2025 systematic review.

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The research shows that obesity, insulin resistance, hypertension, and abnormal lipids raise cardiovascular and diabetes risk, and promote gynaecologic cancers.

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The study highlights the need for better metabolic health and suggests more vigilant screening and targeted interventions for at-risk women.

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Elevated body mass index, often seen in metabolic syndrome, disrupts the delicate hormonal balance in women, particularly increasing estrogen levels.

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Weight management, dietary control, regular exercise, and medications to address metabolic imbalances remain the cornerstone of prevention.